A systematic analysis of gene-gene interaction in multiple sclerosis

• Main Authors: Lotfi Slim (Author), Clément Chatelain (Author), Hélène de Foucauld (Author), Chloé-Agathe Azencott (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background For the most part, genome-wide association studies (GWAS) have only partially explained the heritability of complex diseases. One of their limitations is to assume independent contributions of individual variants to the phenotype. Many tools have therefore been developed to inves...