Evaluating DNA Methylation in Random Fine Needle Aspirates from the Breast to Inform Cancer Risk

• Main Authors: Kala Visvanathan (Author), Ashley Cimino-Mathews (Author), Mary Jo Fackler (Author), Pritesh S. Karia (Author), Christopher J. VandenBussche (Author), Mikiaila Orellana (Author), Betty May (Author), Marissa J. White (Author), Mehran Habibi (Author), Julie Lange (Author), David Euhus (Author), Vered Stearns (Author), John Fetting (Author), Melissa Camp (Author), Lisa Jacobs (Author), Saraswati Sukumar (Author)
• Format: Book
• Published: Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Critical regulatory genes are functionally silenced by DNA hypermethylation in breast cancer and premalignant lesions. The objective of this study was to examine whether DNA methylation assessed in random fine needle aspirates (rFNA) can be used to inform breast cancer risk. Methods. I...