Is there an epigenetic component underlying the resistance of triple-negative breast cancers to PARP inhibitors?
Poly(ADP-ribose)polymerase (Parp) is an enzyme responsible for catalyzing post-translational modifications through the addition of poly(ADP-ribose) chains (known as PARylation). Modification by PARylation modulates numerous cellular processes including transcription, chromatin remodeling, apoptosis...
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Format: | Book |
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Frontiers Media S.A.,
2012-12-01T00:00:00Z.
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A1234.567 |
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