Morus alba L. (Sangzhi) Alkaloids Promote Insulin Secretion, Restore Diabetic β-Cell Function by Preventing Dedifferentiation and Apoptosis

• Main Authors: Lei Lei (Author), Yi Huan (Author), Quan Liu (Author), Caina Li (Author), Hui Cao (Author), Wenming Ji (Author), Xuefeng Gao (Author), Yaxin Fu (Author), Pingping Li (Author), Ruiping Zhang (Author), Zeper Abliz (Author), Yuling Liu (Author), Shuainan Liu (Author), Zhufang Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Morus alba L. (Sangzhi) alkaloids (SZ-A), extracted from the Chinese herb Morus alba L. (mulberry twig), have been shown to ameliorate hyperglycemia in type 2 diabetes and have been approved for diabetes treatment in the clinic. However, their versatile pharmacologic effects and regulator...