Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis.

• Main Authors: Apinya Pumpuang (Author), Susanna J Dunachie (Author), Phornpun Phokrai (Author), Kemajittra Jenjaroen (Author), Kitisak Sintiprungrat (Author), Siriphan Boonsilp (Author), Paul J Brett (Author), Mary N Burtnick (Author), Narisara Chantratita (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Melioidosis is a severe disease caused by Burkholderia pseudomallei. Clinical manifestations are diverse and acute infections require immediate treatment with effective antibiotics. While culture is the current diagnostic standard, it is time-consuming and has low sensitivity. In endemic...