Hyaluronidase Inhibitor-Incorporated Cross-Linked Hyaluronic Acid Hydrogels for Subcutaneous Injection

• Autors principals: Min-Hwan Kim (Autor), Ju-Hwan Park (Autor), Duy-Thuc Nguyen (Autor), Sungyun Kim (Autor), Da In Jeong (Autor), Hyun-Jong Cho (Autor), Dae-Duk Kim (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2021-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Hyaluronidase (HAase) inhibitor-incorporated hyaluronic acid (HA) hydrogel cross-linked with 1,4-butanediol diglycidyl ether (BDDE) was designed to reduce the toxicity risk induced by BDDE and its biodegradation rate in subcutaneous tissue. The formulation composition of hydrogel and its preparation...