Anti-Interleukin-1 Agents in Adult Onset Still's Disease
Interleukin 1β (IL-1β) is emerging as a master mediator of adult onset Still's disease (AOSD) pathogenesis. This pleiotropic cytokine, whose expression is under the control of the inflammasome pathway, has a wide type of effects. As a key mediator of innate immunity is a potent pyrogen and faci...
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Hindawi Limited,
2012-01-01T00:00:00Z.
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