3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity

Mitochondrial toxicity (Mito-Tox) risk has increased due to the administration of several classes of drugs, particularly some life-long antiretroviral drugs for HIV<sup>+</sup> individuals. However, no suitable in vitro assays are available to test long-term Mito-Tox (≥4 weeks). The goal...

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Main Authors: Huifen Ding (Author), Kalyani Jambunathan (Author), Guochun Jiang (Author), David M. Margolis (Author), Iris Leng (Author), Michael Ihnat (Author), Jian-Xing Ma (Author), Jon Mirsalis (Author), Yuanyuan Zhang (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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