Differentially expressed alternatively spliced genes in skeletal muscle from cancer patients with cachexia

• Autores principales: Ashok Narasimhan (Autor), Russell Greiner (Autor), Oliver F. Bathe (Autor), Vickie Baracos (Autor), Sambasivarao Damaraju (Autor)
• Formato: Libro
• Publicado: Wiley, 2018-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Alternative splicing (AS) is a post‐transcriptional gene regulatory mechanism that contributes to proteome diversity. Aberrant splicing mechanisms contribute to various cancers and muscle‐related conditions such as Duchenne muscular dystrophy. However, dysregulation of AS in canc...