Preparation of topical bimatoprost with enhanced skin infiltration and in vivo hair regrowth efficacy in androgenic alopecia

• Main Authors: Laxman Subedi (Author), Prashant Pandey (Author), Jung-Hyun Shim (Author), Ki-Taek Kim (Author), Seung-Sik Cho (Author), Kyo-Tan Koo (Author), Beum Joon Kim (Author), Jin Woo Park (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To prepare a topical formulation of bimatoprost (BIM) with high skin permeability, we designed a solvent mixture system composed of ethanol, diethylene glycol monoethyl ether, cyclomethicone, and butylated hydroxyanisole, serving as a volatile solvent, nonvolatile co-solvent, spreading agent, and an...