Oligomer β-amyloid Induces Hyperactivation of Ras to Impede NMDA Receptor-Dependent Long-Term Potentiation in Hippocampal CA1 of Mice

The activity of Ras, a small GTPase protein, is increased in brains with Alzheimer's disease. The objective of this study was to determine the influence of oligomeric Aβ1-42 on the activation of Ras, and the involvement of the Ras hyperactivity in Aβ1-42-induced deficits in spatial cognition an...

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Main Authors: Ya Wang (Author), Zhaochun Shi (Author), Yajie Zhang (Author), Jun Yan (Author), Wenfeng Yu (Author), Ling Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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