Mutagenicity and antimutagenicity of (−)-hinokinin a trypanosomicidal compound measured by <it>Salmonella</it> microsome and comet assays

• Main Authors: Resende Flávia Aparecida (Author), Barbosa Lilian Cristina (Author), Tavares Denise Crispim (Author), de Camargo Mariana Santoro (Author), de Souza Rezende Karen Cristina (Author), e Silva Márcio Luis de Andrade (Author), Varanda Eliana Aparecida (Author)
• Format: Bog
• Udgivet: BMC, 2012-10-01T00:00:00Z.
• Fag: article
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<p>Abstract</p> <p>Background</p> <p>The dibenzylbutyrolactone lignan (−)-hinokinin (HK) was derived by partial synthesis from (−)-cubebin, isolated from the dry seeds of the pepper, <it>Piper cubeba</it>. Considering the good trypanosomicidal activity of HK...