Primary vaccination with low dose live dengue 1 virus generates a proinflammatory, multifunctional T cell response in humans.
The four dengue virus serotypes (DENV-1-DENV-4) have a large impact on global health, causing 50-100 million cases of dengue fever annually. Herein, we describe the first kinetic T cell response to a low-dose DENV-1 vaccination study (10 PFU) in humans. Using flow cytometry, we found that proinflamm...
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Main Authors: | Janet C Lindow (Author), Nathan Borochoff-Porte (Author), Anna P Durbin (Author), Stephen S Whitehead (Author), Kelly A Fimlaid (Author), Janice Y Bunn (Author), Beth D Kirkpatrick (Author) |
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Format: | Book |
Published: |
Public Library of Science (PLoS),
2012-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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