Troglitazone Inhibits Vascular Endothelial Growth Factor-Induced Angiogenic Signaling via Suppression of Reactive Oxygen Species Production and Extracellular Signal-Regulated Kinase Phosphorylation in Endothelial Cells

• Prif Awduron: Byung Chul Park (Awdur), Dinesh Thapa (Awdur), Jong Suk Lee (Awdur), Su-Young Park (Awdur), Jung-Ae Kim (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2009-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Thiazolidinediones, peroxisome proliferators-activated receptor gamma (PPARγ) ligands, have been recognized as a potential therapeutic agents for the treatment of pathological neovascularization. In the present study, we examined the molecular mechanism by which troglitazone (TROG), a PPARγ agonist,...