A hamster-derived West Nile virus isolate induces persistent renal infection in mice.

• Main Authors: Vandana Saxena (Author), Guorui Xie (Author), Bei Li (Author), Tierra Farris (Author), Thomas Welte (Author), Bin Gong (Author), Paul Boor (Author), Ping Wu (Author), Shao-Jun Tang (Author), Robert Tesh (Author), Tian Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

West Nile virus (WNV) can persist long term in the brain and kidney tissues of humans, non-human primates, and hamsters. In this study, mice were infected with WNV strain H8912, previously cultured from the urine of a persistently infected hamster, to determine its pathogenesis in a murine host.We f...