VEGFR2-targeted antibody fused with IFNαmut regulates the tumor microenvironment of colorectal cancer and exhibits potent anti-tumor and anti-metastasis activity
Although interferon α (IFNα) and anti-angiogenesis antibodies have shown appropriate clinical benefit in the treatment of malignant cancer, they are deficient in clinical applications. Previously, we described an anti-vascular endothelial growth factor receptor 2 (VEGFR2)-IFNα fusion protein named J...
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Main Authors: | Pengzhao Shang (Author), Rui Gao (Author), Yijia Zhu (Author), Xiaorui Zhang (Author), Yang Wang (Author), Minji Guo (Author), Hui Peng (Author), Min Wang (Author), Juan Zhang (Author) |
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Format: | Book |
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Elsevier,
2021-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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