Imidazole and Imidazolium Antibacterial Drugs Derived from Amino Acids

• Main Authors: Adriana Valls (Author), Jose J. Andreu (Author), Eva Falomir (Author), Santiago V. Luis (Author), Elena Atrián-Blasco (Author), Scott G. Mitchell (Author), Belén Altava (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The antibacterial activity of imidazole and imidazolium salts is highly dependent upon their lipophilicity, which can be tuned through the introduction of different hydrophobic substituents on the nitrogen atoms of the imidazole or imidazolium ring of the molecule. Taking this into consideration, we...