Circulating microtranscriptome profiles reveal distinct expression of microRNAs in severe leptospirosis.

• Main Authors: Umaporn Limothai (Author), Janejira Dinhuzen (Author), Titipon Payongsri (Author), Sasipha Tachaboon (Author), Pisit Tangkijvanich (Author), Natthaya Chuaypen (Author), Nattachai Srisawat (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Biomarkers to predict the severity of leptospirosis are still lacking. This study aimed to identify and validate microRNAs in patients with severe leptospirosis, that could potentially be used as biomarkers for predicting an unfavorable outcome. Serum samples were collected from participants with de...