Brusatol Inhibits Proliferation and Invasion of Glioblastoma by Down-Regulating the Expression of ECM1

• Main Authors: Zhang'an Dai (Author), Lin Cai (Author), Yingyu Chen (Author), Silu Wang (Author), Qian Zhang (Author), Chengde Wang (Author), Ming Tu (Author), Zhangzhang Zhu (Author), Qun Li (Author), Xianghe Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brusatol (Bru), a Chinese herbal extract, has a variety of anti-tumor effects. However, little is known regarding its role and underlying mechanism in glioblastoma cells. Here, we found that Bru could inhibit the proliferation of glioblastoma cells in vivo and in vitro. Besides, it also had an inhib...