Population Pharmacokinetics and Pharmacodynamic Target Attainment of Isavuconazole against <i>Aspergillus fumigatus</i> and <i>Aspergillus flavus</i> in Adult Patients with Invasive Fungal Diseases: Should Therapeutic Drug Monitoring for Isavuconazole Be Considered as Mandatory as for the Other Mold-Active Azoles?

• Príomhchruthaitheoirí: Pier Giorgio Cojutti (Údar), Alessia Carnelutti (Údar), Davide Lazzarotto (Údar), Emanuela Sozio (Údar), Anna Candoni (Údar), Renato Fanin (Údar), Carlo Tascini (Údar), Federico Pea (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2021-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Isavuconazole is a newer broad-spectrum triazole approved for the treatment of invasive fungal disease. The objective of this study was to conduct a population pharmacokinetic and pharmacodynamic analysis of isavuconazole in a retrospective cohort of hospitalized patients. A nonlinear mixed-effect a...