Adrenocorticotropic hormone at pathophysiological concentration modulates the proliferation and differentiation of bone cells

• Main Authors: Tsuyoshi Sato (Author), Yoshie Sano (Author), Masahiro Niimura (Author), Shoichiro Kokabu (Author), Michihiko Usui (Author), Tetsuya Yoda (Author)
• Format: Book
• Published: Elsevier, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Adrenocorticotropic hormone (ACTH) plays a vital role in maintaining the function of the hypothalamic-pituitary-adrenal axis. Recent studies have demonstrated that ACTH directly affects the proliferation and differentiation of bone cells. However, the ACTH concentrations used in...