The Carbonic Anhydrase IX inhibitor SLC-0111 as emerging agent against the mesenchymal stem cell-derived pro-survival effects on melanoma cells

• Main Authors: Silvia Peppicelli (Author), Elena Andreucci (Author), Jessica Ruzzolini (Author), Francesca Bianchini (Author), Chiara Nediani (Author), Claudiu T. Supuran (Author), Lido Calorini (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSC) take part to solid tumour-associated stroma and critically influence progression of malignancy. Our study represents a striking example of melanoma progression to a more malignant and resistant phenotype promoted by MSC and the possibility to contrast this diabolic liais...