Multi‐site Investigation of Genetic Determinants of Warfarin Dose Variability in Latinos

• Main Authors: Nihal El Rouby (Author), Leiliane Rodrigues Marcatto (Author), Karla Claudio (Author), Letícia Camargo Tavares (Author), Heidi Steiner (Author), Marianna R. Botton (Author), Steve A. Lubitz (Author), Echo N. Fallon (Author), Kevin Yee (Author), Justin Kaye (Author), Stuart A. Scott (Author), Jason Karnes (Author), Paulo Caleb Junior de Lima Santos (Author), Jorge Duconge (Author), Larisa H. Cavallari (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We conducted a multi‐site investigation of genetic determinants of warfarin dose variability in Latinos from the U.S. and Brazil. Patients from four institutions in the United States (n = 411) and Brazil (n = 663) were genotyped for VKORC1 c.‐1639G> A, common CYP2C9 variants, CYP4F2*3, and NQO1*2...