Immortalizing Mesenchymal Stromal Cells from Aged Donors While Keeping Their Essential Features

• Главные авторы: María Piñeiro-Ramil (Автор), Rocío Castro-Viñuelas (Автор), Clara Sanjurjo-Rodríguez (Автор), Silvia Rodríguez-Fernández (Автор), Tamara Hermida-Gómez (Автор), Francisco J. Blanco-García (Автор), Isaac Fuentes-Boquete (Автор), Silvia Díaz-Prado (Автор)
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• Опубликовано: Hindawi Limited, 2020-01-01T00:00:00Z.
• Предметы: article
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Human bone marrow-derived mesenchymal stromal cells (MSCs) obtained from aged patients are prone to senesce and diminish their differentiation potential, therefore limiting their usefulness for osteochondral regenerative medicine approaches or to study age-related diseases, such as osteoarthiritis (...