Optimization of Pramipexole-Loaded In Situ Thermosensitive Intranasal Gel for Parkinson's Disease

• المؤلفون الرئيسيون: Rushi Trivedi (مؤلف), Vahid Vikram Minglani (مؤلف), Ahmed M. El-Gazzar (مؤلف), Gaber El-Saber Batiha (مؤلف), Mohamed H. Mahmoud (مؤلف), Mitesh Patel (مؤلف), Meenakshi Patel (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The objective of the present work was to develop and optimize an intranasal in situ gel of Pramipexole dihydrochloride for enhanced drug delivery, better patient acceptability, and possible proper treatment of Parkinson's disease. Preliminary studies were performed to select formulation compone...