Characterization of cooperative PS-oligo activation of human TLR9
Single-stranded phosphorothioate oligonucleotides (PS-oligos) can activate TLR9, leading to an innate immune response. This can occur with PS-oligos containing unmethylated CpG sites, the canonical motif, or PS-oligos that do not contain those motifs (non-CpG). Structural evidence shows that TLR9 co...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Elsevier,
2023-09-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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