The Use of the Target Trial Approach in Perinatal Pharmacoepidemiology: A Scoping Review Protocol

• Main Authors: Lisiane Freitas Leal (Author), Sonia Marzia Grandi (Author), Daniel Marques Mota (Author), Paulo José Gonçalves Ferreira (Author), Genevieve Gore (Author), Robert William Platt (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pregnant and postpartum women have been historically excluded from clinical trials, with data on the safety of drugs relying on observational research. Methodological concerns regarding the timing and dosing of medications, data sources, study designs, and methods used for estimating ass...