Comparing Model Performance in Characterizing the PK/PD of the Anti‐Myostatin Antibody Domagrozumab

• मुख्य लेखकों: Abhinav Tiwari (लेखक), Indranil Bhattacharya (लेखक), Phylinda L.S. Chan (लेखक), Lutz Harnisch (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Modeling and simulation provides quantitative information on target coverage for dose selection. Optimal model selection often relies on fit criteria and is not necessarily mechanistically driven. One such case is discussed where healthy volunteer data of an anti‐myostatin monoclonal antibody domagr...