Comparing Model Performance in Characterizing the PK/PD of the Anti‐Myostatin Antibody Domagrozumab

• Asıl Yazarlar: Abhinav Tiwari (Yazar), Indranil Bhattacharya (Yazar), Phylinda L.S. Chan (Yazar), Lutz Harnisch (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Modeling and simulation provides quantitative information on target coverage for dose selection. Optimal model selection often relies on fit criteria and is not necessarily mechanistically driven. One such case is discussed where healthy volunteer data of an anti‐myostatin monoclonal antibody domagr...