ERK Inhibitor Enhances Everolimus Efficacy through the Attenuation of dNTP Pools in Renal Cell Carcinoma

The clinical efficiency of everolimus, an mammalian target of rapamycin (mTOR) inhibitor, is palliative as sequential or second-line therapy for renal cell carcinoma (RCC). However, the limited response of everolimus in RCC remains uncertain. In the present study, everolimus-resistant RCC models wer...

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Main Authors: Yun Zou (Author), Wenzhi Li (Author), Juan Zhou (Author), Jin Zhang (Author), Yiran Huang (Author), Zhong Wang (Author)
Format: Book
Published: Elsevier, 2019-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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