Silencing of the PHLDA1 leads to global proteome changes and differentiation pathways of human neuroblastoma cells

• Main Authors: Beata Bugara (Author), Małgorzata Durbas (Author), Maja Kudrycka (Author), Agata Malinowska (Author), Irena Horwacik (Author), Hanna Rokita (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroblastoma (NB) is the most common extracranial pediatric solid tumor originating from the abnormal development of cells of the sympathoadrenal lineage of the neural crest. Targeting GD2 ganglioside (GD2), a glycolipid expressed on neuroblastoma cells, with GD2 ganglioside-recognizing antibodies...