High-Mobility Group Nucleosome-Binding Protein 1 Mediates Renal Fibrosis Correlating with Macrophages Accumulation and Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy Mice Model

• Auteurs principaux: Jiali Yu (Auteur), Rong Dong (Auteur), Jingjing Da (Auteur), Jiayu Li (Auteur), Fuxun Yu (Auteur), Yan Zha (Auteur)
• Format: Livre
• Publié: Karger Publishers, 2019-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background/Aim: Renal fibrosis is essential for the progression of diabetic nephropathy (DN). Macrophages accumulate in diabetic kidneys and are involved in epithelial-to-mesenchymal transition (EMT), a vital mechanism leading to renal fibrosis. Recently, high-mobility group nucleosome-binding prote...