Identification of Metabolomic Signatures for Ischemic Hypoxic Encephalopathy Using a Neonatal Rat Model

• Main Authors: Yulia Shevtsova (Author), Chupalav Eldarov (Author), Natalia Starodubtseva (Author), Kirill Goryunov (Author), Vitaliy Chagovets (Author), Oleg Ionov (Author), Egor Plotnikov (Author), Denis Silachev (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A study was performed to determine early metabolomic markers of ischemic hypoxic encephalopathy (HIE) using a Rice-Vannucci model for newborn rats. Dried blood spots from 7-day-old male and female rat pups, including 10 HIE-affected animals and 16 control animals, were analyzed by liquid chromatogra...