Sclareol Inhibits Hypoxia-Inducible Factor-1α Accumulation and Induces Apoptosis in Hypoxic Cancer Cells

Purpose: The hypoxia in solid tumors is associated with the resistance to chemo/radiotherapy.Hypoxia-inducible factor-1 (HIF-1) plays a key role in cell remodeling to hypoxia. Therefore, theinhibition of HIF-1 accumulation is considered a hopeful strategy for the treatment of cancer.Here, we aimed t...

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Ngā kaituhi matua: Somayeh Vandghanooni (Author), Zahra Farajzadeh Vahid (Author), Ailar Nakhlband (Author), Mir Babak Bahadori (Author), Morteza Eskandani (Author)
Hōputu: Pukapuka
I whakaputaina: Tabriz University of Medical Sciences, 2022-05-01T00:00:00Z.
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