Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy

• Váldodahkkit: Chunhui Jiang (Dahkki), Yefei Wen (Dahkki), Kazuki Kuroda (Dahkki), Kevin Hannon (Dahkki), Michael A. Rudnicki (Dahkki), Shihuan Kuang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: The Company of Biologists, 2014-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Duchenne muscular dystrophy (DMD) is a devastating disease characterized by muscle wasting, loss of mobility and death in early adulthood. Satellite cells are muscle-resident stem cells responsible for the repair and regeneration of damaged muscles. One pathological feature of DMD is the progressive...