Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training

• Main Authors: Mark R. Viggars (Author), Hannah E. Berko (Author), Stuart J. Hesketh (Author), Christopher A. Wolff (Author), Miguel A. Gutierrez-Monreal (Author), Ryan A. Martin (Author), Isabel G. Jennings (Author), Zhiguang Huo (Author), Karyn A. Esser (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: In this investigation, we addressed the contribution of the core circadian clock factor, BMAL1, in skeletal muscle to both acute transcriptional responses to exercise and transcriptional remodeling in response to exercise training. Additionally, we adopted a systems biology approach to in...