Role of sigma-1 receptors in neurodegenerative diseases

• Asıl Yazarlar: Linda Nguyen (Yazar), Brandon P. Lucke-Wold (Yazar), Shona A. Mookerjee (Yazar), John Z. Cavendish (Yazar), Matthew J. Robson (Yazar), Anna L. Scandinaro (Yazar), Rae R. Matsumoto (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2015-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Neurodegenerative diseases with distinct genetic etiologies and pathological phenotypes appear to share common mechanisms of neuronal cellular dysfunction, including excitotoxicity, calcium dysregulation, oxidative damage, ER stress and mitochondrial dysfunction. Glial cells, including microglia and...