In Vitro Methodologies for Evaluating Colon-Targeted Pharmaceutical Products and Industry Perspectives for Their Applications

• Egile Nagusiak: Mauricio A. García (Egilea), Felipe Varum (Egilea), Jozef Al-Gousous (Egilea), Michael Hofmann (Egilea), Susanne Page (Egilea), Peter Langguth (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Several locally acting colon-targeted products to treat colonic diseases have been recently developed and marketed, taking advantage of gastrointestinal physiology to target delivery. Main mechanisms involve pH-dependent, time-controlled and/or enzymatic-triggered release. With site of action locate...