miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair

• Главные авторы: Yanan Lu (Автор), Shuting Song (Автор), Xiaoxue Jiang (Автор), Qiuyu Meng (Автор), Chen Wang (Автор), Xiaonan Li (Автор), Yuxin Yang (Автор), Xiaoru Xin (Автор), Qidi Zheng (Автор), Liyan Wang (Автор), Hu Pu (Автор), Xin Gui (Автор), Tianming Li (Автор), Dongdong Lu (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2019-03-01T00:00:00Z.
• Предметы: article
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miR675 is highly expressed in several human tumor tissues and positively regulates cell progression. Herein, we demonstrate that miR675 promotes malignant transformation of human mesenchymal stem cells. Mechanistically, we reveal that miR675 enhances the expression of the polyubiquitin-binding prote...