Immunoproteomic analysis of a Chikungunya poxvirus-based vaccine reveals high HLA class II immunoprevalence.

• Main Authors: Elena Lorente (Author), Alejandro Barriga (Author), Eilon Barnea (Author), Concepción Palomo (Author), Juan García-Arriaza (Author), Carmen Mir (Author), Mariano Esteban (Author), Arie Admon (Author), Daniel López (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Efficient adaptive antiviral cellular and humoral immune responses require previous recognition of viral antigenic peptides bound to human leukocyte antigen (HLA) class I and II molecules, which are exposed on the surface of infected and antigen presenting cells, respe...