Benefits and harms of polygenic risk scores in organised cancer screening programmes: a cost-effectiveness analysisResearch in context

• Hauptverfasser: Changfa Xia (Verfasst von), Yongjie Xu (Verfasst von), He Li (Verfasst von), Siyi He (Verfasst von), Wanqing Chen (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2024-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Summary: Background: While polygenic risk scores (PRS) could enable the streamlining of organised cancer screening programmes, its current discriminative ability is limited. We conducted a cost-effectiveness analysis to trade-off the benefits and harms of PRS-stratified cancer screening in China. Me...