Albumin-EDTA-Vanadium Is a Powerful Anti-Proliferative Agent, Following Entrance into Glioma Cells via Caveolae-Mediated Endocytosis

• Hauptverfasser: Itzik Cooper (Verfasst von), Orly Ravid (Verfasst von), Daniel Rand (Verfasst von), Dana Atrakchi (Verfasst von), Chen Shemesh (Verfasst von), Yael Bresler (Verfasst von), Gili Ben-Nissan (Verfasst von), Michal Sharon (Verfasst von), Mati Fridkin (Verfasst von), Yoram Shechter (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2021-09-01T00:00:00Z.
• Schlagworte: article
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Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. In this study, we prepared a monomodified derivative of HSA covalently linked to an EDTA derivative and investigated its efficacy to shuttle weakly anti-proliferative EDTA associating ligands such as...