Albumin-EDTA-Vanadium Is a Powerful Anti-Proliferative Agent, Following Entrance into Glioma Cells via Caveolae-Mediated Endocytosis

• Main Authors: Itzik Cooper (Author), Orly Ravid (Author), Daniel Rand (Author), Dana Atrakchi (Author), Chen Shemesh (Author), Yael Bresler (Author), Gili Ben-Nissan (Author), Michal Sharon (Author), Mati Fridkin (Author), Yoram Shechter (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. In this study, we prepared a monomodified derivative of HSA covalently linked to an EDTA derivative and investigated its efficacy to shuttle weakly anti-proliferative EDTA associating ligands such as...