Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition

• Asıl Yazarlar: Malavika Deodhar (Yazar), Sweilem B. Al Rihani (Yazar), Lucy Darakjian (Yazar), Jacques Turgeon (Yazar), Veronique Michaud (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Fluoxetine is still one of the most widely used antidepressants in the world. The drug is extensively metabolized by several cytochrome P450 (CYP450) enzymes and subjected to a myriad of CYP450-mediated drug interactions. In a multidrug regimen, preemptive mitigation of drug-drug interactions requir...