In silico evaluation of some 4-(quinolin-2-yl)pyrimidin-2-amine derivatives as potent V600E-BRAF inhibitors with pharmacokinetics ADMET and drug-likeness predictions

Abstract Background The resistance of V600E-BRAF to the vemurafenib and the side effects of the identified inhibitors trigger the research for a novel and more potent anti-melanoma agents. In this study, virtual docking screening along with pharmacokinetics ADMET and drug-likeness predictions were c...

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Váldodahkkit: Abdullahi Bello Umar (Dahkki), Adamu Uzairu (Dahkki), Gideon Adamu Shallangwa (Dahkki), Sani Uba (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: SpringerOpen, 2020-09-01T00:00:00Z.
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