In silico evaluation of some 4-(quinolin-2-yl)pyrimidin-2-amine derivatives as potent V600E-BRAF inhibitors with pharmacokinetics ADMET and drug-likeness predictions
Abstract Background The resistance of V600E-BRAF to the vemurafenib and the side effects of the identified inhibitors trigger the research for a novel and more potent anti-melanoma agents. In this study, virtual docking screening along with pharmacokinetics ADMET and drug-likeness predictions were c...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
SpringerOpen,
2020-09-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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