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Atrial-selective block of sodium channels by acehytisine in rabbit myocardium

Acehytisine, a multi-ion channel blocker, can markedly inhibit INa, ICa, IKur, If at various concentrations and effectively terminate and prevent atrial fibrillation (AF) in patients and animal models, but the molecular mechanism underlying its blockage remains elusive. In this study, we investigate...

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Main Authors: Xinrong Fan (Author), Chao Wang (Author), Na Wang (Author), Xianhong Ou (Author), Hanxiong Liu (Author), Yan Yang (Author), Xitong Dang (Author), Xiaorong Zeng (Author), Lin Cai (Author)
Format: Book
Published: Elsevier, 2016-12-01T00:00:00Z.
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