Comparative pharmacokinetics of tetramethylpyrazine phosphate in rat plasma and extracellular fluid of brain after intranasal, intragastric and intravenous administration

• المؤلفون الرئيسيون: Dongmei Meng (مؤلف), Haoyang Lu (مؤلف), Shanshan Huang (مؤلف), Minyan Wei (مؤلف), Pingtian Ding (مؤلف), Xianglin Xiao (مؤلف), Yuehong Xu (مؤلف), Chuanbin Wu (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2014-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The purpose of this study was to compare the pharmacokinetic profiles of tetramethylpyrazine phosphate (TMPP) in plasma and extracellular fluid of the cerebral cortex of rats via three delivery routes: intranasal (i.n.), intragastric (i.g.) and intravenous (i.v.) administration. After i.n., i.g. and...