CLSTN3 gene variant associates with obesity risk and contributes to dysfunction in white adipose tissue

• Main Authors: Ningning Bai (Author), Xuhong Lu (Author), Li Jin (Author), Miriayi Alimujiang (Author), Jingyuan Ma (Author), Fan Hu (Author), Yuejie Xu (Author), Jingjing Sun (Author), Jun Xu (Author), Rong Zhang (Author), Junfeng Han (Author), Cheng Hu (Author), Ying Yang (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: White adipose tissue (WAT) possesses the remarkable remodeling capacity, and maladaptation of this ability contributes to the development of obesity and associated comorbidities. Calsyntenin-3 (CLSTN3) is a transmembrane protein that promotes synapse development in brain. Even though this...