NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs

• Main Authors: Xin Zhang (Author), Siting Hong (Author), Shuhan Qi (Author), Wenxiu Liu (Author), Xiaohui Zhang (Author), Zhiyu Shi (Author), Wenjia Chen (Author), Meng Zhao (Author), Xinhua Yin (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing evidence suggests that the NLRP3 (nucleotide oligomerization domain-like receptor family, pyrin domain containing 3) inflammasome participates in cardiovascular diseases. However, its role and activation mechanism during hypertension remains unclear. In this study, we tested the role and...