Design and synthesis of new indole drug candidates to treat Alzheimer's disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy
A novel series of indole-based compounds was designed, synthesised, and evaluated as anti-Alzheimer's and anti-neuroinflammatory agents. The designed compounds were in vitro evaluated for their AChE and BuChE inhibitory activities. The obtained results revealed that compound 3c had higher selec...
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Main Authors: | Phoebe F. Lamie (Author), Maha M. Abdel-Fattah (Author), John N. Philoppes (Author) |
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Format: | Book |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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