Reduced frequency and functional defects of CD4+CD25highCD127low/− regulatory T cells in patients with unexplained recurrent spontaneous abortion
Abstract Background Unexplained recurrent spontaneous abortion (URSA) is defined as two or more consecutive pregnancy losses, generally of unknown cause; it is related to a failure of fetal-maternal immunological tolerance. Regulatory T cells (Tregs) exert immunosuppressive effects, which are essent...
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BMC,
2020-06-01T00:00:00Z.
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